Belén Rueda

as Ana de Mendoza

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Eduard Fernández

as Felipe II

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Hugo Silva

as Antonio Pérez

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Roberto Enríquez

as Juan de Escobedo

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Michelle Jenner

as Ana de Austria

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Nathalie Poza

as Sofonisba Anguissola

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Álex Angulo

as Núñez de Arce

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Pedro Casablanc

as Mateo Vázquez

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Petra Martínez

as Bernardina

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Nuria Mencía

as Juana de Coello

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Ferran Rañé

as Padre Chaves

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